Search results for "Base Ratio"

showing 2 items of 2 documents

Synthesis of a New Fluorinated Oxazolidinone and Its Reactivity as a Chiral Auxiliary in Aldol Reactions.

2007

A new enantiomerically pure fluorinated oxazolidinone has been prepared from a fluorinated imidoyl chloride and an optically pure sulfoxide. The diastereoselective reduction of the β-iminosulfoxide thus formed followed by elimination of the sulfoxide and cyclization of the created aminoalcohol furnishes the desired product. The fluorinated oxazolidinone was subsequently used as a chiral auxiliary in Aldol reactions. We also found that the selective formation of the syn-Evans and syn-non-Evans diastereoisomer can be controlled by adjusting the Lewis acid/base ratio.

Chiral auxiliaryImidoyl chlorideorganic chemicalsOrganic ChemistryEnantioselective synthesisDiastereomerSulfoxideGeneral MedicineBiochemistryCombinatorial chemistryInorganic Chemistrychemistry.chemical_compoundchemistryAldol reactionEnvironmental ChemistryOrganic chemistryBase Ratioheterocyclic compoundsReactivity (chemistry)Lewis acids and basesPhysical and Theoretical ChemistryChemInform
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Microscopic Insights Into the Formation of Methanesulfonic Acid–Methylamine–Ammonia Particles Under Acid-Rich Conditions

2022

Understanding the microscopic mechanisms of new particle formation under acid-rich conditions is of significance in atmospheric science. Using quantum chemistry calculations, we investigated the microscopic formation mechanism of methanesulfonic acid (MSA)–methylamine (MA)–ammonia (NH3) clusters. We focused on the binary (MSA)2n-(MA)n and ternary (MSA)3n-(MA)n-(NH3)n, (n = 1–4) systems which contain more acid than base molecules. We found that the lowest-energy isomers in each system possess considerable thermodynamic and dynamic stabilities. In studied cluster structures, all bases are protonated, and they form stable ion pairs with MSA, which contribute to the charge transfer and the stab…

aerosolitbase ratio [acid]proton transferEcologyammoniakkipienhiukkasetilmakemiahappamuusklusteritnew particle formationrikkiyhdisteetacid-rich conditiontyppiyhdisteetmethanesulfonic acid–methylamine–ammonia particlesEcology Evolution Behavior and SystematicsFrontiers in Ecology and Evolution
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